Extrapolation- Meaning for those not included in the investigation

1. To similar individuals, groups or populations
Do the investigators extrapolate or extend the conclusions to individuals, groups, or populations that are similar to those who participated in the investigation?

2. Beyond the data
Do the investigators extrapolate by extending the conclusions beyond the dose, duration, or other characteristics of the investigation?

3. To other populations
Do the investigators extrapolate to populations or settings that are quite different from those in the investigation?