Studying a Study Testing a Test Rating a Rate Considering Costs   • MAARIE Framework   Cost Effectiveness Article Guide to the Guidelines Selecting a Statistic Test Yourself	Extrapolation- Conclusions for other populations 1. To similar populations Is the meaning for the average individual as well as the aggregate population impact addressed? 2. Beyond the data If extrapolation beyond the data is conducted, is only a linear extrapolation used and are marginal effects of scale of operation considered? 3. To other populations If extrapolation to other populations is conducted, are differences from the target population of the investigation considered?